Biochemical and Functional Characterization of Rpa2 N-Terminal Phosphorylation during DNA Repair and Checkpoint Adaptation in Saccharomyces Cerevisiae
In response to DNA damage, a signaling cascade is activated within cells that promotes cell cycle arrest in order to provide adequate time for DNA repair to occur. Replication Factor A (RFA) is an essential, heterotrimeric complex that acts as a primary sensor of DNA damage, localizes to sites of an...
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| Format: | Others |
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North Dakota State University
2018
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| Online Access: | https://hdl.handle.net/10365/27482 |