Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations

京都大学 === 0048 === 新制・課程博士 === 博士(医科学) === 甲第22379号 === 医科博第109号 === 新制||医科||7(附属図書館) === 京都大学大学院医学研究科医科学専攻 === (主査)教授 遊佐 宏介, 教授 武田 俊一, 教授 近藤 玄 === 学位規則第4条第1項該当 === Doctor of Medical Science === Kyoto University === DFAM...

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Main Author: Janin, Grajcarek
Other Authors: 遊佐, 宏介
Format: Doctoral Thesis
Language:English
Published: Kyoto University 2020
Subjects:
491
Online Access:http://hdl.handle.net/2433/253215
id ndltd-kyoto-u.ac.jp-oai-repository.kulib.kyoto-u.ac.jp-2433-253215
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spelling ndltd-kyoto-u.ac.jp-oai-repository.kulib.kyoto-u.ac.jp-2433-2532152021-09-06T05:12:35Z Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations ゲノムワイドなマイクロホモロジーを活用した正確かつテンプレートフリーなヒト欠失変異のゲノム編集技術の開発 Janin, Grajcarek 遊佐, 宏介 武田, 俊一 近藤, 玄 ジャニン, グラジュカレク DNA double-strand break repair Microhomology-mediated end joining (MMEJ) Genome editing using CRISPR/Cas9 Human induced pluripotent stem cells (hiPSCs) Disease modelling 491 京都大学 0048 新制・課程博士 博士(医科学) 甲第22379号 医科博第109号 新制||医科||7(附属図書館) 京都大学大学院医学研究科医科学専攻 (主査)教授 遊佐 宏介, 教授 武田 俊一, 教授 近藤 玄 学位規則第4条第1項該当 Doctor of Medical Science Kyoto University DFAM 2020-07-31T05:34:29Z 2020-07-31T05:34:29Z 2020-03-23 2020-03-23 doctoral thesis Thesis or Dissertation http://hdl.handle.net/2433/253215 14301甲第22379号 10.14989/doctor.k22379 14301 eng https://doi.org/10.1038/s41467-019-12829-8 NATURE COMMUNICATIONS | (2019) 10:4856 | https://doi.org/10.1038/s41467-019-12829-8 | application/pdf Kyoto University 京都大学
collection NDLTD
language English
format Doctoral Thesis
sources NDLTD
topic DNA double-strand break repair
Microhomology-mediated end joining (MMEJ)
Genome editing using CRISPR/Cas9
Human induced pluripotent stem cells (hiPSCs)
Disease modelling
491
spellingShingle DNA double-strand break repair
Microhomology-mediated end joining (MMEJ)
Genome editing using CRISPR/Cas9
Human induced pluripotent stem cells (hiPSCs)
Disease modelling
491
Janin, Grajcarek
Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations
description 京都大学 === 0048 === 新制・課程博士 === 博士(医科学) === 甲第22379号 === 医科博第109号 === 新制||医科||7(附属図書館) === 京都大学大学院医学研究科医科学専攻 === (主査)教授 遊佐 宏介, 教授 武田 俊一, 教授 近藤 玄 === 学位規則第4条第1項該当 === Doctor of Medical Science === Kyoto University === DFAM
author2 遊佐, 宏介
author_facet 遊佐, 宏介
Janin, Grajcarek
author Janin, Grajcarek
author_sort Janin, Grajcarek
title Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations
title_short Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations
title_full Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations
title_fullStr Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations
title_full_unstemmed Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations
title_sort genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations
publisher Kyoto University
publishDate 2020
url http://hdl.handle.net/2433/253215
work_keys_str_mv AT janingrajcarek genomewidemicrohomologiesenableprecisetemplatefreeeditingofbiologicallyrelevantdeletionmutations
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