Bacterial Cell Wall Synthases Require Outer Membrane Lipoprotein Cofactors
To fortify their cytoplasmic membrane and protect it from osmotic rupture, most bacteria surround themselves with a peptidoglycan (PG) exoskeleton. The PG synthases that build this structure are called penicillin-binding proteins (PBPs). Since they are the targets of penicillin and related antibioti...
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| Language: | en_US |
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Harvard University
2012
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| Online Access: | http://dissertations.umi.com/gsas.harvard:10146 http://nrs.harvard.edu/urn-3:HUL.InstRepos:9547905 |