Familial ALS Proteins Function in Prevention/repair of Transcription-Associated DNA Damage

Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron dysfunction disease that leads to paralysis and death. There is currently no defined molecular pathogenesis pathway. Multiple proteins involved in RNA processing are linked to ALS, including FUS and TDP43; and we propose a disease m...

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Bibliographic Details
Main Author: Hill, Sarah J.
Format: Others
Language:en
Published: Harvard University 2016
Online Access:http://nrs.harvard.edu/urn-3:HUL.InstRepos:27007760