A natural allelic series of complex structural variants and its influence on the risk of lupus and schizophrenia

The human genome's strongest influences on two common diseases, systemic lupus erythematosus (SLE) and schizophrenia, arise from genetic variation in the Human Leukocyte Antigen (HLA) locus. However, the genes and functional alleles driving these genetic relationships have remained unknown. We...

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Bibliographic Details
Main Author: Sekar, Aswin
Other Authors: McCarroll, Steven A.
Language:en_US
Published: Harvard University 2014
Subjects:
Online Access:http://dissertations.umi.com/gsas.harvard.inactive:11728
http://nrs.harvard.edu/urn-3:HUL.InstRepos:13070061