A natural allelic series of complex structural variants and its influence on the risk of lupus and schizophrenia
The human genome's strongest influences on two common diseases, systemic lupus erythematosus (SLE) and schizophrenia, arise from genetic variation in the Human Leukocyte Antigen (HLA) locus. However, the genes and functional alleles driving these genetic relationships have remained unknown. We...
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Language: | en_US |
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Harvard University
2014
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Online Access: | http://dissertations.umi.com/gsas.harvard.inactive:11728 http://nrs.harvard.edu/urn-3:HUL.InstRepos:13070061 |