Neutrophil human Fcg Receptor IIA and the b2 integrin Mac-1 cross-talk in autoimmune disease
Systemic lupus erythematosus (SLE) is a chronic multiorgan autoimmune disorder characterized by abundant immune complex (IC) deposition, with nephritis being a major cause of morbidity and mortality. Yet, IC deposition alone is not sufficient for disease development suggesting that additional factor...
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Language: | en_US |
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Harvard University
2014
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Online Access: | http://dissertations.umi.com/gsas.harvard:11461 http://nrs.harvard.edu/urn-3:HUL.InstRepos:12274121 |