Deciphering the biological functions of F-box proteins through the use of Parallel Adaptor Capture (PAC) proteomics.
The timely and selective proteasomal degradation of proteins is important for the maintenance of proper cellular processes. Prior to proteasomal degradation, proteins destined for degradation are polyubiquitiylated by ubiquitin ligases (E3s). The SKP1-CUL1-F-box protein (SCF) complex is a member o...
| Main Author: | |
|---|---|
| Other Authors: | |
| Language: | en_US |
| Published: |
Harvard University
2013
|
| Subjects: | |
| Online Access: | http://dissertations.umi.com/gsas.harvard:11164 http://nrs.harvard.edu/urn-3:HUL.InstRepos:11181126 |