Structural Characterization of BCL-2 Family Protein Interactions Using Photoreactive Stapled Peptides and Mass Spectrometry

Structural Characterization of BCL-2 Family Protein Interactions Using Photoreactive Stapled Peptides and Mass Spectrometry

Recent improvements in mass spectrometry instrumentation have stimulated the fusion of this technology with protein crosslinking to advance the structural proteomics field. However, analysis of complex datasets from crosslinking experiments remains a bottleneck. The majority of crosslinking studies...

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Bibliographic Details
Main Author: Braun, Craig Ronald
Other Authors: Walensky, Loren David
Language:en_US
Published: Harvard University 2013
Subjects:
biochemistry
biology
apoptosis
cancer
crosslinking
photoaffinity
proteomics
Online Access:http://dissertations.umi.com/gsas.harvard:10139
http://nrs.harvard.edu/urn-3:HUL.InstRepos:10333319

Internet

http://dissertations.umi.com/gsas.harvard:10139
http://nrs.harvard.edu/urn-3:HUL.InstRepos:10333319

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