Targeting the Kv1.3 Ion Channel with Peptide Inhibitors and Nanoparticle Bioconjugates: Neuromodulation of the Olfactory Bulb and Its Influence on Whole-Body Metabolism
Electrical signaling in the olfactory bulb (OB) is modulated by changes in metabolic state. The voltage-gated potassium channel, Kv1.3, makes up 60 - 80% of the outward current flow in mitral cells (MCs), the primary projection neurons of the OB. The metabolic molecules GLP-1, insulin, and glucose a...
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| Format: | Others |
| Language: | English English |
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Florida State University
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| Online Access: | http://purl.flvc.org/fsu/fd/2018_Su_Schwartz_fsu_0071E_14755 |