Investigation of the Effects of G9a Knockout on Subnuclear Localization and Replication Timing of G9a Repressed Genes When Integrated into an Early Replicating Region
G9a is a histone methyltransferase that is responsible for dimethylation of histone 3 lysine 9 (H3K9me2) this chromatin marker is typically associated with transcriptional silencing. Following conditional knockout of G9a in mouse embryonic stem cells, genes that are regulated by G9a are strongly upr...
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| Format: | Others |
| Language: | English English |
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Florida State University
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| Online Access: | http://purl.flvc.org/fsu/fd/FSU_migr_etd-0634 |