Within Study Dependence in Meta-Analysis: Comparison of GLS Method and Multilevel Approaches

Multivariate meta-analysis methods typically assume the dependence of effect sizes. One type of experimental-design study that generates dependent effect sizes is the multiple-endpoint study. While the generalized least squares (GLS) approach requires the sample covariance between outcomes...

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Bibliographic Details
Other Authors: Lee, Seungjin (authoraut)
Format: Others
Language:English
English
Published: Florida State University
Subjects:
Online Access:http://purl.flvc.org/fsu/fd/FSU_migr_etd-9205
Description
Summary:Multivariate meta-analysis methods typically assume the dependence of effect sizes. One type of experimental-design study that generates dependent effect sizes is the multiple-endpoint study. While the generalized least squares (GLS) approach requires the sample covariance between outcomes within studies to deal with the dependence of the effect sizes, the univariate three-level approach does not require the sample covariance to analyze such multivariate effect-size data. Considering that it is rare that primary studies report the sample covariance, if the two approaches produce the same estimates and corresponding standard errors, the univariate three-level model approach could be an alternative to the GLS approach. The main purpose of this dissertation was to compare these two approaches under the random-effects model for synthesizing standardized mean differences in multiple-endpoints experimental designs using a simulation study. Two data sets were generated under the random-effects model: one set with two outcomes and the other set with five outcomes. The simulation study in this dissertation found that the univariate three-level model yielded the appropriate parameter estimates and their standard errors corresponding to those in the multivariate meta-analysis using the GLS approach. === A Dissertation submitted to the Department of Educational Psychology and Learning Systems in partial fulfillment of the requirements for the degree of Doctor of Philosophy. === Fall Semester, 2014. === November 6, 2014. === effect sizes, gls, meta-analysis, multilevel, multivariate === Includes bibliographical references. === Betsy Jane Becker, Professor Directing Dissertation; Fred Huffer, University Representative; Insu Paek, Committee Member; Yanyun Yang, Committee Member.