An Investigation into the Adduct Forming Potential of Drugs of Abuse with Peptides and Proteins
Hemoglobin and serum albumin, two prevalent proteins in human blood, contain unbound cysteine thiol moieties, creating a nucleophilic site with the potential for covalent modification by reactive chemical species. These covalent modifications, called “adducts”, are stable entities that accumulate du...
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| Format: | Others |
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FIU Digital Commons
2018
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| Online Access: | https://digitalcommons.fiu.edu/etd/3869 https://digitalcommons.fiu.edu/cgi/viewcontent.cgi?article=5211&context=etd |