In search of MMP specific inhibitors: protein engineering of TIMPs
The tissue inhibitors of metalloproteinases (TIMPs) are endogenous inhibitors of the matrix metalloproteinases (MMPs). Since unregulated MMP activities are linked to arthritis, cancer, and atherosclerosis, TIMP variants that are selective inhibitors of disease-related MMPs have potential therapeutic...
| Other Authors: | |
|---|---|
| Format: | Others |
| Language: | English |
| Published: |
Florida Atlantic University
|
| Subjects: | |
| Online Access: | http://purl.flvc.org/FAU/221942 |