Molecular characterization of an Arabidopsis SH3 domain-containing protein.
在真核细胞中,细胞自噬是一个将细胞物质吞噬到自噬体降解的保守的代谢过程。自噬体起始于自噬前体结构(PAS) 并由其逐渐扩展和延伸形成其最后的双膜结构,最后和溶酶体(lysosome)或液泡(vacuole)融合得以降解。在酵母和动物细胞中,研究已发现一系列自噬体相关基因(ATG)蛋白参与调控自噬体的形成。自噬体形成的相关研究存在两个主要的未解决的问题,它们包括自噬体的膜来源和膜变形机制。而在植物中,相当一部分关键的自噬体同源蛋白的缺失导致其分子机制研究仍处于初步阶段。在本研究中,我主要通过利用SH3P2,一个N 端含有BAR (Bin-Amphiphysin-Rvs) 结构域及C 端含有SH3...
Other Authors: | Zhuang, Xiaohong |
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Format: | Others |
Language: | English Chinese |
Published: |
2013
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Subjects: | |
Online Access: | http://library.cuhk.edu.hk/record=b5934663 http://repository.lib.cuhk.edu.hk/en/item/cuhk-328390 |
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