Pattern recognition lectins in normal and abnormal pregnancy.

• Other Authors: Lui, Wai Ting.
• Format: Others
• Language: English; Chinese
• Published: 2008
• Subjects: Lectins; Pregnancy
• Online Access: http://library.cuhk.edu.hk/record=b5893564; http://repository.lib.cuhk.edu.hk/en/item/cuhk-326456

Lui, Wai Ting. === Thesis (M.Phil.)--Chinese University of Hong Kong, 2008. === Includes bibliographical references (leaves 96-106). === Abstracts in English and Chinese. === Abstract --- p.i === Acknowledgements --- p.v === Table of Content --- p.vii === List of Tables --- p.x === List of Figures --- p.xi === Publications --- p.xiii === Chapter Chapter 1 --- Innate Immunity --- p.1 === Chapter 1.1 --- Immunity --- p.1 === Chapter 1.1.1 --- Surface Barriers --- p.2 === Chapter 1.1.2 --- Cell-mediated Innate Immunity --- p.2 === Chapter 1.1.3 --- Humoral Innate Immunity --- p.3 === Chapter 1.2 --- Complement System --- p.4 === Chapter 1.2.1 --- The Classical Pathway --- p.5 === Chapter 1.2.2 --- The Alternative Pathway --- p.6 === Chapter 1.2.3 --- The lectin pathway --- p.7 === Chapter 1.3 --- Lectins --- p.8 === Chapter 1.3.1 --- Mannose binding lectin --- p.11 === Chapter 1.3.2 --- Ficolin --- p.11 === Chapter 1.3.2.1 --- L-ficolin --- p.12 === Chapter 1.3.2.2 --- H-ficolin --- p.12 === Chapter 1.3.2.3 --- M-ficolin --- p.13 === Chapter Chapter 2 --- Innate Immunity in Pregnancy --- p.15 === Chapter 2.1 --- Immune challenge --- p.15 === Chapter 2.2 --- Natural Antimicrobials --- p.15 === Chapter 2.3 --- Cell-mediated Immunity --- p.16 === Chapter 2.4 --- Humoral Immunity --- p.18 === Chapter Chapter 3 --- Current Study --- p.20 === Chapter 3.1 --- Aim and Objectives --- p.20 === Chapter 3.2 --- General Methodology --- p.21 === Chapter Chapter 4 --- Pattern recognition lectins in maternal liver and lung --- p.23 === Chapter 4.1 --- Introduction --- p.23 === Chapter 4.2 --- Materials and Methods --- p.23 === Chapter 4.2.1 --- Animals --- p.23 === Chapter 4.2.2 --- Protein extraction --- p.27 === Chapter 4.2.3 --- Antibodies --- p.27 === Chapter 4.2.4 --- Western Blot --- p.28 === Chapter 4.2.5 --- Immunohistochemistry --- p.29 === Chapter 4.3 --- Results --- p.31 === Chapter 4.3.1 --- Temporal expression of lectins in maternal liver in mice --- p.31 === Chapter 4.3.2 --- Temporal expression of lectins in maternal lung in mice --- p.31 === Chapter 4.3.3 --- Spatial expression of lectins in maternal liver in mice --- p.34 === Chapter 4.3.4 --- Spatial expression of lectins in maternal lung in mice --- p.37 === Chapter 4.4 --- Discussion --- p.39 === Chapter 4.5 --- Conclusion --- p.40 === Chapter Chapter 5 --- Pattern recognition lectins in endometrium --- p.42 === Chapter 5.1 --- Introduction --- p.42 === Chapter 5.2 --- Materials and Methods --- p.43 === Chapter 5.2.1 --- Animals --- p.43 === Chapter 5.2.2 --- Immunohistochemistry --- p.45 === Chapter 5.3 --- Results --- p.45 === Chapter 5.4 --- Discussion --- p.48 === Chapter 5.5 --- Conclusion --- p.50 === Chapter Chapter 6 --- Pattern recognition lectins in maternal-fetal interface --- p.51 === Chapter 6.1 --- Introduction --- p.51 === Chapter 6.2 --- Materials and Methods --- p.52 === Chapter 6.2.1 --- Animals --- p.52 === Chapter 6.2.2 --- Immunohistochemistry --- p.55 === Chapter 6.3 --- Results --- p.55 === Chapter 6.4 --- Discussion --- p.58 === Chapter 6.5 --- Conclusion --- p.59 === Chapter Chapter 7 --- Pattern recognition lectins in preeclampsia --- p.60 === Chapter 7.1 --- Introduction --- p.60 === Chapter 7.2 --- Materials and Methods --- p.62 === Chapter 7.2.1 --- Patients --- p.62 === Chapter 7.2.2 --- Protein extraction --- p.63 === Chapter 7.2.3 --- Western Blot --- p.63 === Chapter 7.2.4 --- Lectin immunohistochemistry --- p.64 === Chapter 7.2.5 --- Apoptosis immunohistochemistry --- p.65 === Chapter 7.3 --- Results --- p.66 === Chapter 7.3.1 --- Expression levels of ficolins in normal and preeclamptic placenta --- p.67 === Chapter 7.3.2 --- Spatial expression of ficolins in normal and preeclamptic placenta --- p.68 === Chapter 7.3.3 --- Co-localization of Fas and ficolins in preeclamptic placenta --- p.69 === Chapter 7.4 --- Discussion --- p.71 === Chapter 7.5 --- Conclusion --- p.75 === Chapter Chapter 8 --- Pattern recognition lectins in miscarriage --- p.76 === Chapter 8.1 --- Introduction --- p.76 === Chapter 8.2 --- Materials and Methods --- p.77 === Chapter 8.2.1 --- Patients --- p.77 === Chapter 8.2.2 --- Immunohistochemistry --- p.78 === Chapter 8.3 --- Results --- p.79 === Chapter 8.3.1 --- Spatial expression of lectins in normal placenta and placenta from miscarriage patients --- p.80 === Chapter 8.3.2 --- Spatial expression of lectins in normal decidua and decidua from miscarriage patients --- p.86 === Chapter 8.4 --- Discussion --- p.92 === Chapter 8.5 --- Conclusion --- p.93 === Chapter Chapter 9 --- Future plan --- p.94 === References --- p.96