Molecular mechanisms involved in induction of cell growth arrest and cell death in human colon cancer cells by tangutorine, a b-carboline.

• Other Authors: Liu, Bonnie Pui-ling.
• Format: Others
• Language: English; Chinese
• Published: 2004
• Subjects: Colon (Anatomy) > Cancer > Prevention; Colon (Anatomy) > Cancer > Treatment; Colonic Neoplasms > prevention & control
• Online Access: http://library.cuhk.edu.hk/record=b5896368; http://repository.lib.cuhk.edu.hk/en/item/cuhk-324980

Liu Bonnie Pui-ling. === Thesis (M.Phil.)--Chinese University of Hong Kong, 2004. === Includes bibliographical references (leaves 134-163). === Abstracts in English and Chinese. === Acknowledgments --- p.i === Abbreviations --- p.ii === Abstract === English --- p.1 === Chinese --- p.3 === Chapter Chapter 1 --- General Introduction === Chapter 1.1 --- Colorectal Cancer Statistics --- p.5 === Chapter 1.2 --- Colon Cancer --- p.5 === Chapter 1.3 --- Treatment --- p.6 === Chapter 1.4 --- Effects of Cytotoxic Drug Treatment --- p.7 === Chapter 1.5 --- Cell Cycle --- p.8 === Chapter 1.6 --- Oxidases --- p.9 === Chapter 1.7 --- Chemistry of Novel β-carboline: Tangutorine --- p.11 === Chapter 1.8 --- Aim of Study --- p.14 === Chapter Chapter 2 --- Cytotoxicity === Chapter 2.1 --- Introduction --- p.15 === Chapter 2.2 --- Materials and Methods --- p.18 === Chapter 2.3 --- Results --- p.23 === Chapter 2.4 --- Discussion --- p.44 === Chapter Chapter 3 --- Oxidase Activity and Protein Oxidation === Chapter 3.1 --- Introduction --- p.48 === Chapter 3.2 --- Materials and Methods --- p.54 === Chapter 3.3 --- Results --- p.60 === Chapter 3.4 --- Discussion --- p.80 === Chapter Chapter 4 --- Cell Cycle === Chapter 4.1 --- Introduction --- p.89 === Chapter 4.2 --- Materials and Methods --- p.93 === Chapter 4.3 --- Results --- p.96 === Chapter 4.4 --- Discussion --- p.118 === Chapter Chapter 5 --- General Discussion --- p.126 === References --- p.134