Synthetic studies towards acarbose: syntheses of N,O,O,O,O-pentaacetylvalienamine and N,O,O,O,O-pentaacety1-2-epi-valienamine.

• Other Authors: Li, Tin Yau.
• Format: Others
• Language: English
• Published: Chinese University of Hong Kong 1996
• Subjects: Glucosidases > Antagonists & inhibitors; Glucosidases > Biosynthesis
• Online Access: http://library.cuhk.edu.hk/record=b5888918; http://repository.lib.cuhk.edu.hk/en/item/cuhk-321524

by Li Tin Yau. === Thesis (M.Phil.)--Chinese University of Hong Kong, 1996. === Includes bibliographical references (leaves 56-60). === Acknowledgment --- p.i === Table of Contents --- p.ii === Abstract --- p.iii === Abbreviation --- p.iv === Chapter I --- Introduction --- p.1 === Chapter I-1 --- General Background --- p.1 === Chapter I-2 --- Mechanistic Aspect of Glycosidase Inhibition --- p.4 === Chapter I-3 --- Previous Syntheses of Valienamine and its Diastereomers --- p.7 === Chapter II --- Results and Discussion --- p.16 === Chapter II-1 --- General Strategy --- p.16 === Chapter II-2 --- Synthesis of Tribenzyl ether69 --- p.18 === Chapter II-3 --- Synthesis of Diol67 --- p.20 === Chapter II-4 --- "Synthesis of N,O,O, O, O-Pentaacetylvalienamine30 and its 2-Epimer62" --- p.22 === Chapter II-5 --- Synthesis of Diacetate66 --- p.26 === Chapter II-6 --- Synthesis of the Valienamine Derivatives 63 and64 --- p.30 === Chapter III --- Conclusion --- p.34 === Chapter IV --- Experimental --- p.36 === Chapter V --- Reference --- p.56