The Pharmacokinetics of some anti-tuberculous drugs.

• Other Authors: Walubo, Andrew.
• Format: Others
• Language: English
• Published: Chinese University of Hong Kong 1991
• Subjects: Antitubercular Agents > pharmacokinetics; Pharmacokinetics
• Online Access: http://library.cuhk.edu.hk/record=b5886906; http://repository.lib.cuhk.edu.hk/en/item/cuhk-318820

by Walubo Andrew. === Thesis (M.Phil.)--Chinese University of Hong Kong, 1991. === Bibliography: leaves 148-174. === ABSTRACT --- p.i === declaration --- p.iv === acknowledgements --- p.v === Chapter chapter 1 --- general introduction --- p.1 === Chapter chapter 2 --- literature review --- p.5 === Chapter section 1 --- isoniazid --- p.5 === Chapter section 2 --- rifampicin --- p.19 === Chapter section 3 --- pyrazinamide --- p.27 === Chapter section 4 --- an overview of the use of antituberculous drugs in uganda and hong kong --- p.30 === Chapter section 5 --- review of analytical methods --- p.40 === Chapter section 6 --- conclusions from the reviews --- p.44 === Chapter chapter 3 --- some principles of pharmacokinetics --- p.47 === Chapter section 1 --- introduction --- p.47 === Chapter section 2 --- application of pharmacokinetics --- p.55 === Chapter chapter 4. --- aims of the present project --- p.66 === Chapter chapter 5 --- chromatographic methods --- p.68 === Chapter section 1 --- a simultaneous assay for isoniazid and hydrazine metabolite in plasma and cerebrospinal fluid in the rabbit --- p.68 === Chapter section 2 --- a simultaneous assay for rifampicin and pyrazinamide in human plasma --- p.89 === Chapter chapter 6 --- the pharmacokinetics of isoniazid and hydrazine metabolite in the plasma and cerebrospinal fluid of rabbits --- p.91 === Chapter chapter 7 --- the disposition of anti-tuberculous drugs in the plasma of elderly patients --- p.108 === Chapter SECTION 1 --- METHODS --- p.109 === Chapter SECTION 2 --- CLINICAL ASSESSMENT --- p.112 === Chapter SECTION 3 --- GENERAL FINDINGS. --- p.117 === Chapter 1)- --- THE DISPOSITION OF ISONIAZID AND HYDRAZINE METABOLITE IN THE PLASMA OF ELDERLY PATIENTS --- p.117 === Chapter 2) - --- "THE DISPOSITION OF ISONIAZID, PYRAZINAMIDE AND RIFAMPICIN IN THE PLASMA OF ELDERLY PATIENTS" --- p.129 === Chapter SECTION 4 --- CASE REPORT --- p.139 === Chapter CHAPTER 8 --- p.145 === Chapter SECTION 1 --- GENERAL CONCLUSIONS --- p.145 === Chapter SECTION 2 --- FUTURE STUDIES --- p.147 === REFERENCES --- p.148 === APPENDICES: --- p.AO === Chapter APPENDIX A --- (WORK SHEETS) --- p.AO === Chapter APPENDIX B --- (SCIENTIFIC COMMUNICATIONS) --- p.BO