Computational Studies of Nanodiamond-Membrane Association and Membrane Inserted Fluorescent Probe
对于生物物理研究而言,探究细胞膜本身的性质以及与之相关的生物动力学特性一直是一个非常重要的课题。本论文将会涉及两个有关细胞膜的研究:其一,结合自由能计算和连续体模型的研究方法,我们探讨了作为细胞跨膜运输主要机制的胞吞作用。在这项研究中,我们主要关注纳米金刚石与细胞膜的相互作用,建立了纳米金刚石表明曲率、粘附强度以及膜卷曲能量之间的相互关系;其二,我们分析并比较了两种电压敏感染色剂分子的构象。电压敏感染色剂分子在细胞膜中的构象会影响它测量电压的敏感程度。为了提高这种电压敏感分子的测量水平,我们定义了不同角度来描述两种具不同分子结构的染色剂分子在磷脂双分子膜中的构象,并说明了对称的分子结构对于提升...
Other Authors: | Yin, Hang (author.) |
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Format: | Others |
Language: | English Chinese |
Published: |
2016
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Subjects: | |
Online Access: | http://repository.lib.cuhk.edu.hk/en/item/cuhk-1292340 |
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