Mechanisms and therapeutic targeting of NT5C2 mutations in relapsed acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is an aggressive hematologic malignancy that results from the unregulated growth of B-cell and T-cell lymphoid progenitors. Despite the implementation of risk-stratification and improved multi-agent therapeutic regimens, 20% of pediatric and 50% of adult patients f...

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Bibliographic Details
Main Author: Dieck, Chelsea
Language:English
Published: 2019
Subjects:
Online Access:https://doi.org/10.7916/d8-y5g9-9573