Human T-cell Negative Selection in Health and Disease
Thymic negative selection has been identified as a crucial checkpoint in thymocyte development that purges the T-cell repertoire of autoreactive T cells through apoptosis of the cells after strong T cell receptor (TCR) stimulation. It has been well established that efficient thymic negative selectio...
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| Language: | English |
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2021
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| Online Access: | https://doi.org/10.7916/d8-sqg7-9058 |