Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to mediate VEGFR2 expression in breast cancer cells

Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to mediate VEGFR2 expression in breast cancer cells

Mutant p53 impacts the expression of numerous genes at the level of transcription to mediate oncogenesis. To investigate how mutant p53 impacts transcription, we studied how mutant p53 regulates vascular endothelial growth factor receptor 2 (VEGFR2), one of its strongest target genes that we identif...

Full description

Bibliographic Details
Main Author: Pfister, Neil Thomas
Language:English
Published: 2015
Subjects:
Vascular endothelial growth factors
Transcription factors
Mutation (Biology)
Oncology
Molecular biology
Medicine
Online Access:https://doi.org/10.7916/D8H130R1

Internet

https://doi.org/10.7916/D8H130R1

Similar Items