3-Phosphoinositide-dependent kinase-1 (PDK1)-mediated signaling regulates hematopoietic stem cell (HSC) quiesence by governing the oxidative response

Regulation of hematopoiesis through the finite control of hematopoietic stem cell (HSC) quiescence and proliferation is critical to the health of the organism since disturbances in blood production can lead to clinical malignancies such as anemia or leukemia. Therefore, elucidating the processes tha...

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Bibliographic Details
Main Author: Matsushima, Danielle Erina
Language:English
Published: 2016
Subjects:
Online Access:https://doi.org/10.7916/D8GT5NCB