PTEN affects gene expression and histone modifications and plays a role in the regulation of transcription
Phosphatase and tensin homologue deleted on chromosome ten (PTEN) is one of the most commonly altered tumor suppressors in human cancer. It is a dual-specificity phosphatase that by converting the lipid second messenger PIP3 to PIP2 antagonizes the PI3K/AKT signaling pathway. PTEN also has numerous,...
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| Language: | English |
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2017
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| Online Access: | https://doi.org/10.7916/D8GH9W9R |