Chloride Intracellular Channels 1 and 4 function in distinct branches of S1P signaling to regulate endothelial cell behavior and vascular development
Chloride intracellular channels (CLICs), 1 and 4 are expressed in endothelial cells where they promote cell proliferation, migration and vessel morphogenesis in vitro. Clic4-/- mice exhibit defects in retinal angiogenesis suggesting CLIC4 functions as an angiogenic regulator. S1P signaling, through...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
2016
|
| Subjects: | |
| Online Access: | https://doi.org/10.7916/D8736QWV |