Nanoscale Electrical and Coarse-grained Molecular Dynamics Studies of Influenza Hemagglutinin-mediated Membrane Fusion Pores

Fusion of viral and host membranes is a key step during infection by membrane-enclosed viruses. The fusion pore plays a critical role, and must dilate to release the viral genome. Prior studies of fusion mediated by influenza A hemagglutinin (HA) revealed ~2-5 nm pores that flickered before dilating...

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Bibliographic Details
Main Author: Alcott, Brett Eugene
Language:English
Published: 2017
Subjects:
Online Access:https://doi.org/10.7916/D85B0DS9