Computational Studies of Acidic Destabilization and Membrane Association of Diphtheria Toxin Translocation (T) Domain

Diphtheria toxin translocation (T) domain is a water soluble protein that consists of ten alpha-helices in high pH solution. Experimental studies have determined that T-domain undergoes conformational changes upon decrease of solution pH, which shifts the protein population from its initial water so...

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Bibliographic Details
Main Author: Flores-Canales, Jose C.
Format: Others
Published: Research Showcase @ CMU 2014
Online Access:http://repository.cmu.edu/dissertations/1038
http://repository.cmu.edu/cgi/viewcontent.cgi?article=2077&context=dissertations

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