Identification of Modulators of OGlycosylation Using Isoform-Specific Sensors for GalNAc Transferase Activity
Humans express at least twenty isoforms of GalNAc transferase (termed GalNAc-T1 to T20) that localize to the Golgi apparatus and initiate mucin-type O-glycosylation. Regulation of this family of enzymes affects the function of a vast array of cellular proteins transiting the secretory pathway. This...
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| Format: | Others |
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Research Showcase @ CMU
2016
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| Online Access: | http://repository.cmu.edu/dissertations/943 http://repository.cmu.edu/cgi/viewcontent.cgi?article=1982&context=dissertations |