Substrate specificity and mutational studies of KDO8PS

The enzyme 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) catalyses the stereospecific aldol-like condensation between phosphoenolpyruvate (PEP) and the five-carbon sugar D-arabinose 5-phosphate (A5P). This is the first biosynthetic step in the formation of 3-deoxy-D-manno-octulosonate (...

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Bibliographic Details
Main Author: Allison, Timothy Murray
Language:en
Published: University of Canterbury. Chemistry 2012
Subjects:
Online Access:http://hdl.handle.net/10092/6684