Substrate specificity and mutational studies of KDO8PS
The enzyme 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) catalyses the stereospecific aldol-like condensation between phosphoenolpyruvate (PEP) and the five-carbon sugar D-arabinose 5-phosphate (A5P). This is the first biosynthetic step in the formation of 3-deoxy-D-manno-octulosonate (...
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Language: | en |
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University of Canterbury. Chemistry
2012
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Online Access: | http://hdl.handle.net/10092/6684 |