Probing the mechanism of dihydrodipicolinate synthase

Dihydrodipicolinate synthase (DHDPS, E.C. 4.2.1.52) is the enzyme that catalyses the first committed step in the lysine biosynthetic pathway, which involves the condensation reaction between (S)-aspartate β-semialdehyde ((S)-ASA) and pyruvate via a ping-pong mechanism, and is feedback inhibited by l...

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Bibliographic Details
Main Author: Soares da Costa, Tatiana Pereira
Language:en
Published: University of Canterbury. School of Biological Sciences 2010
Online Access:http://hdl.handle.net/10092/4296