Mitigation of aberrant CK2 expression in various cancer types
CK2 is a serine/threonine kinase, with 2 catalytic subunits (α and α’) and 2 regulatory subunits (β). CK2 phosphorylates and activates substrates in several pathways implicated in cancer progression such as PI3K/AKT, NF-κB, and JAK/STAT pathways; thus increased CK2 activity can promote cancer growt...
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| Language: | en_US |
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2021
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| Online Access: | https://hdl.handle.net/2144/43459 |