SMAD signaling and airway cell fate determination

BACKGROUND: Goblet cell hyperplasia is a key feature of asthma and other airway diseases. It is likely regulated by the BMP/TGF-b/SMAD signaling pathway which is expressed in low levels in basal and goblet cells but highly active in other differentiated cell types. Therefore, SMAD signaling may b...

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Bibliographic Details
Main Author: Wilson-Mifsud, Brittany
Other Authors: Hawkins, Finn
Language:en_US
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/2144/42341