Co-registration of paired histological sections and MRI scans of the rabbit larynx

Co-registering images of different modalities, termed intermodal image registration, is an important tool in improving our understanding of how certain features detectable in one modality might manifest in the other. However, structural changes – usually the result of tissue processing or noise in i...

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Bibliographic Details
Main Author: Nirody, Eshan Ashok
Other Authors: Wisco, Jonathan J.
Language:en_US
Published: 2020
Subjects:
MRI
Online Access:https://hdl.handle.net/2144/41339
Description
Summary:Co-registering images of different modalities, termed intermodal image registration, is an important tool in improving our understanding of how certain features detectable in one modality might manifest in the other. However, structural changes – usually the result of tissue processing or noise in image acquisition – can make matching difficult. In this thesis, I outline a pre-processing protocol for co-registration of paired histological sections and MRI scans as well as discuss different co-registration strategies using the rabbit larynx as a model system.