Recombinase-based genetic circuits in human T cells for cellular immunotherapy

Treatments using a patient’s own T cells to target cancer have applied advances in genetic engineering and cancer immunotherapy as the basis for a powerful, targeted cell-based therapy. Tumor-infiltrating lymphocytes and T cells that have been genetically modified to express cancer antigen-specific...

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Bibliographic Details
Main Author: Chakravarti, Deboki
Other Authors: Wong, Wilson W.
Language:en_US
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/2144/30728