Experimental candidiasis in mice: evaluation of the histopathology and the effect of cysteine on the virulence of candida albicans
Thesis (M.A.)--Boston University. === Normal strains of Candida albicans reproduce by budding when conditions are favorable for growth. In animal tissues a rapid morphological chance takes place budding cells fail to detach and pseudouyphae develop. The addition of cysteine to the normal growth med...
| Main Author: | |
|---|---|
| Language: | en_US |
| Published: |
Boston University
2018
|
| Online Access: | https://hdl.handle.net/2144/28116 |
| id |
ndltd-bu.edu-oai-open.bu.edu-2144-28116 |
|---|---|
| record_format |
oai_dc |
| spelling |
ndltd-bu.edu-oai-open.bu.edu-2144-281162019-01-08T15:44:01Z Experimental candidiasis in mice: evaluation of the histopathology and the effect of cysteine on the virulence of candida albicans De Palma, Philip A Thesis (M.A.)--Boston University. Normal strains of Candida albicans reproduce by budding when conditions are favorable for growth. In animal tissues a rapid morphological chance takes place budding cells fail to detach and pseudouyphae develop. The addition of cysteine to the normal growth medium of a genetically blocked, filamentous strain of Candida albicans results in a suppresion of the filamentous phase and an increased number of budding yeast forms. Filamentous variants of Candida albicans have not demonstrated appreciable virulence in experimental infections, but tLere is evidence that induced yeast growth under the influence of cysteine accompanies an increase in virulence. 2018-04-05T17:29:10Z 2018-04-05T17:29:10Z 1962 1962 Thesis/Dissertation b14565316 https://hdl.handle.net/2144/28116 en_US Based on investigation of the BU Libraries' staff, this work is free of known copyright restrictions. Boston University |
| collection |
NDLTD |
| language |
en_US |
| sources |
NDLTD |
| description |
Thesis (M.A.)--Boston University. === Normal strains of Candida albicans reproduce by budding when conditions are favorable for growth. In animal tissues a rapid morphological chance takes place budding cells fail to detach and pseudouyphae develop.
The addition of cysteine to the normal growth medium of a genetically blocked, filamentous strain of Candida albicans results in a suppresion of the filamentous phase and an increased number of budding yeast forms. Filamentous variants of Candida albicans have not demonstrated appreciable virulence in experimental infections, but tLere is evidence that induced yeast growth under the influence of cysteine accompanies an increase in virulence. |
| author |
De Palma, Philip A |
| spellingShingle |
De Palma, Philip A Experimental candidiasis in mice: evaluation of the histopathology and the effect of cysteine on the virulence of candida albicans |
| author_facet |
De Palma, Philip A |
| author_sort |
De Palma, Philip A |
| title |
Experimental candidiasis in mice: evaluation of the histopathology and the effect of cysteine on the virulence of candida albicans |
| title_short |
Experimental candidiasis in mice: evaluation of the histopathology and the effect of cysteine on the virulence of candida albicans |
| title_full |
Experimental candidiasis in mice: evaluation of the histopathology and the effect of cysteine on the virulence of candida albicans |
| title_fullStr |
Experimental candidiasis in mice: evaluation of the histopathology and the effect of cysteine on the virulence of candida albicans |
| title_full_unstemmed |
Experimental candidiasis in mice: evaluation of the histopathology and the effect of cysteine on the virulence of candida albicans |
| title_sort |
experimental candidiasis in mice: evaluation of the histopathology and the effect of cysteine on the virulence of candida albicans |
| publisher |
Boston University |
| publishDate |
2018 |
| url |
https://hdl.handle.net/2144/28116 |
| work_keys_str_mv |
AT depalmaphilipa experimentalcandidiasisinmiceevaluationofthehistopathologyandtheeffectofcysteineonthevirulenceofcandidaalbicans |
| _version_ |
1718812822649962496 |