The LKB1-SIK pathway: dysregulation in melanomagenesis and regulated use in skin cancer prevention
The presence of dark melanin (eumelanin) within human epidermis represents one of the strongest predictors of skin cancer risk. Topical rescue of eumelanin synthesis, previously achieved in “redhaired” Mc1r-deficient mice, demonstrated significant protection against UV damage and skin carcinogenesis...
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| Language: | en_US |
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2018
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| Online Access: | https://hdl.handle.net/2144/26493 |