Impact of clinically used alendronate (Fosamax) on cancer-bone metastasis and bone biology revealed by novel 3D-bone organ model systems
OBJECTIVE: Determine the impact of clinically used anti-resorption drug alendronate (ALN) on bone cells and the capacity of bone to regenerate, and to provide insights into the interplay between cancer stem cells and osteocytes/osteoblasts and mesenchymal stem cells using a three-dimensional (3D) li...
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| Language: | en_US |
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2018
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| Online Access: | https://hdl.handle.net/2144/26222 |