Characterization on interactions between the prion protein and amyloid-beta
The cellular prion protein (PrP) has been shown to act as a receptor for soluble oligomers of amyloid-beta (Aβ), an ~4 kDa amyloidogenic peptide that is found in neuritic plaques that are a pathological hallmark of Alzheimer’s disease (AD). Oligomeric forms of the Aβ peptide are thought to be synapt...
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| Language: | en_US |
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2017
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| Online Access: | https://hdl.handle.net/2144/23563 |