Evaluating the role of the Hippo pathway in the onset and disease progression of the SOD1 mouse model of amyotrophic lateral sclerosis

The Hippo pathway is a cell signaling pathway involved in organ size regulation and tumorigenesis in mammals. This pathway regulates the activity of Yes-associated protein (YAP), a transcriptional coactivator which binds to the transcription factor TEAD to promote expression of genes controlling gro...

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Bibliographic Details
Main Author: Granucci, Eric
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/16829