Structure and mechanism to function: allosteric activation of phosphomannomutase 1 and substrate selectivity in Hotdog Fold thioesterases

Two superfamilies were used to explore the structure/function relationship as it pertains to enzyme specificity. The structures and mechanisms of phosphatases belonging to the Haloalkanoate Dehalogenase Superfamily (HADSF) and thioesterases of the Hotdog Fold Superfamily (HDFSF) were determined usi...

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Bibliographic Details
Main Author: Ji, Tianyang
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/15703