The role of interferon regulatory factor-5 in systemic lupus erythematosus (SLE) and SLE-associated atherosclerosis

Gain-of-function polymorphisms in the gene encoding human interferon regulatory factor-5 (IRF5) are associated with an increase in risk for the development of the autoimmune disease Systemic Lupus Erythematosus (SLE). IRF5 is a transcription factor that participates in the activation of the immune...

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Bibliographic Details
Main Author: Watkins, Amanda Ann
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/14319