Molecular pathways controlling DNA damage response

P53 is inactivated in around 50 % of human neoplasms and more than 26,000 somatic mutations of the p53 have reported in human cancers. P53 network is activated after cells are exposed to the DNA damage and depending on diverse conditions and type of DNA damage, p53 upregulation could lead to repress...

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Bibliographic Details
Main Author: Alhebshi, H.
Published: University of Salford 2018
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.766345

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