Characterisation of TPL-2 signalling pathways in innate immunity
The MAP 3-kinase TPL-2 is required for activation of ERK1/2 MAP kinases in macrophages after stimulation of Toll-like receptors and the receptors for TNF and IL-1β. TPL-2 drives inflammation in a number of autoimmune and inflammatory disease models, and consequently is considered a potential anti-in...
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University College London (University of London)
2015
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.763051 |