The GENVABO study : genetic variants as biomarkers of jaw osteonecrosis associated with bisphosphonates : a large, multicentre genome-wide association study and detailed analyses of clinical phenotype

Osteonecrosis of the jaw (ONJ) is a potentially severe adverse effect of bisphosphonates. It can cause persistent pain and infection to the jawbones, and is currently considered incurable. ONJ occurs in a subset of individuals exposed to bisphosphonates (≤7%). Although a number of clinical risk fact...

Full description

Bibliographic Details
Main Author: Fung, P. L.
Other Authors: Fedele, S. ; Porter, S. R.
Published: University College London (University of London) 2015
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.763050