Biosynthetic studies and combinatorial biosynthesis of pleuromutilin antibiotics

Pleuromutilin has potential as a next-generation antibiotic, and many semi-synthetic pleuromutilin derivatives have been developed. Recently, characterization of individual enzymatic steps involved in the production of pleuromutilin has been carried out. A linear pathway of pleuromutilin biosynthesi...

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Bibliographic Details
Main Author: Khairudin, Khairunisa
Other Authors: Bailey, Andy ; Foster, Gary
Published: University of Bristol 2018
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.761103