Role of carbonic anhydrase catalysis and gap junctional coupling in regulating ph in pancreatic ductal adenocarcinoma (PDAC)

Role of carbonic anhydrase catalysis and gap junctional coupling in regulating ph in pancreatic ductal adenocarcinoma (PDAC)

Pancreatic ductal adenocarcinoma (PDAC) develops from the acinar cells of the exocrine pancreas. PDAC tumours are hypoxic and produce a characteristically acidic microenvironment hypothesised to favour more aggressive phenotypes. My thesis work concerned the acid-handling mechanisms in 2-D (monolaye...

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Bibliographic Details
Main Author:	Dovmark, Tobias Højgaard
Other Authors:	Vaughan-Jones, Richard D. ; Swietach, Pawel
Published:	University of Oxford 2017
Online Access:	https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.757706

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