The role of Vax1 in craniofacial development

Holoprosencephaly (HPE) is a clinically heterogeneous developmental anomaly affecting the CNS and face, in which the embryonic forebrain fails to divide into distinct halves. Numerous genetic loci and environmental factors are implicated in HPE, but mutation in the sonic hedgehog (Shh) gene is an es...

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Bibliographic Details
Main Author: Geoghegan, Finn Edward
Other Authors: Cobourne, Martyn Timothy ; Liu, Karen Jasmine
Published: King's College London (University of London) 2018
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.754953