Summary: | The aim of this research was to investigate the effects of oral soy-derived phosphatidylserine (S-PtdSer) supplementation on the physiological responses to exercise, exercise performance/capacity and recovery following exercise. The results from this research provide evidence that short-term supplementation with 750 mg.d-1 S-PtdSer: 1. does not influence concentrations of cortisol or adrenocorticosteroid hormone in the circulation in young active male subjects. These data suggest that the current supplementation regime does not affect exercise-induced changes in the hypothalamo-pituitary-adrenal (HPA) axis. 2. is ineffective in attenuating the deleterious effects of exercise on perceived soreness, muscle damage, inflammation and oxidative stress in young active male subjects following eccentric exercise with a relatively low metabolic demand. 3. improved exercise capacity following intermittent cycling and tended to improve performance during prolonged intermittent running. These findings suggest that S-PtdSer might possess potential ergogenic properties. However, the mechanism(s) responsible for these findings remain to be determined.
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