Aggregation and conformation of alpha-synuclein : effects of ligand binding and phosphomimetics
Parkinson’s disease (PD) affects 1 in 500 of the UK population. A critical step in disease aetiology is the formation of Lewy bodies (LBs), deposits of aggregated alpha-synuclein (αsyn) as amyloid inclusions, within surviving neurons. It is well established that αsyn within LBs has undergone a varie...
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Sheffield Hallam University
2017
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Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.749550 |