Aggregation and conformation of alpha-synuclein : effects of ligand binding and phosphomimetics

Parkinson’s disease (PD) affects 1 in 500 of the UK population. A critical step in disease aetiology is the formation of Lewy bodies (LBs), deposits of aggregated alpha-synuclein (αsyn) as amyloid inclusions, within surviving neurons. It is well established that αsyn within LBs has undergone a varie...

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Bibliographic Details
Main Author: Paskins, Aimee Rebecca
Other Authors: Smith, David
Published: Sheffield Hallam University 2017
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.749550