Statistical methodology for evaluation of time-to-event surrogate and true endpoints in small-sample meta-analysis of clinical trials

Clinical trials can be lengthy and costly, with new treatments taking more than a decade to become available to the patients who need them. It is therefore of great interest to improve efficiency in this process, such as replacing the primary endpoint of a clinical trial with an alternative endpoint...

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Bibliographic Details
Main Author: Dimier, Natalie
Published: University of Reading 2017
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.749337